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BIOlogical Neurons CUlture Recognition (BIONCUR™)

 

The matrices for generating electrical stimuli and collecting responses from neuronal cultures are increasingly evolved and miniaturized.

The most ambitious goals foresee the use of neuronal cultures for data storage. We are still far from these goals and there are innumerable problems that need to be solved in order to obtain this result in a practically usable way. One of the fundamental steps is the ability to distinguish two different neuronal cultures on the basis of the electrical stimulus and the electrical response they give on special electrode arrays. One of the possible approaches to obtain such discrimination can be the analysis of stimulus and response images on the matrices using Deep Learning algorithms. The disadvantage of this approach is that each new dataset requires a retake of all previously acquired data.

We have used Mythos™ algorithm which analyzes tens of thousands of stimulus-response matrices but has the ability to learn new stimulus-response associations in real time without cycling on previously acquired data. The Proof Of Concept was based on the simulation of the response of neuronal cultures through pseudo-random sequences whose seed was associated to each particular neural culture.

 

 

 

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